Cancer Cell Line Encyclopedia Database
The cancer cell line encyclopedia ccle project started in 2008 as a collaboration between the broad institute and the novartis institutes for biomedical research and its genomics institute of the novartis research foundation.
Cancer cell line encyclopedia database. Citation s barretina j et al. The goal is to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models to develop integrated computational analyses that. Cosmic the catalogue of somatic mutations in cancer is the world s largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer. 2020 the broad institute of mit harvard.
The original cancer cell line encyclopedia ccle is expanded with deeper characterization of over 1 000 cell lines including genomic transcriptomic and proteomic data and integration with. The ccle cancer cell line encyclopedia project is a collaboration between the broad institute and the novartis institutes for biomedical research and its genomics institute of the novartis research foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models to develop integrated computational analyses that link distinct pharmacologic. Data and scientific tools from many of our cancer research projects can now be accessed via broad data software and tools. The cancer cell line encyclopedia presents the first results from a large scale screen of some 947 cancer cell lines with 24 anticancer drugs with the aim of identifying specific genomic.
2012 the cancer cell line encyclopedia enables predictive modelling of anticancer drug sensitivity. The cancer cell line encyclopedia is a database of gene expression genotype and drug sensitivity data for human cancer cell lines. Cell lines project v92 released 27 aug 20. You may have been redirected here from the broad cancer program resource gateway which is no longer active.
Call for cancer cell models we wouldn t be able to build depmap without the help of the many collaborators and partners who have already shared their cell lines and organoids.
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